Successful treatment of malignant thymoma with sacrum metastases

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چکیده

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Natural history and treatment of malignant thymoma.

Thymomas are rare, slow-growing neoplasms that are considered to be malignant because of their potential invasiveness. The most widely used staging system is that of Masaoka and colleagues, which takes into account the extent of clinical and histopathologically determined disease involvement. However, recent data suggest that the staging system of the French Study Group on Thymic Tumors (GETT s...

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Natural History and Treatment of Malignant Thymoma

The thymus gland is a lymphatic organ involved in lymphoid cell development and maturation. However, its embryologic origins come from the endoderm as epithelial outgrowths of the lower portion of the third pharyngeal pouches. Cells of these epithelial outgrowths grow into the surrounding mesenchyma and subsequently constitute the medullary areas of the lobules of the thymus. In some areas, epi...

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Successful treatment with cyclosporine of thymoma-related aplastic anemia.

Aplastic anemia is a rare immune-mediated complication of thymoma. Thymomas, especially of the cortical type, have the capacity to generate mature T-cells from their immature precursors. Furthermore, mature intratumorous T-cells have an increased autoantigen-specific potential. We present the case of a 75-year-old patient with an inoperable cortical thymoma who developed aplastic anemia 7 years...

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Surgical treatment of primary malignant tumors of the sacrum.

OBJECTIVES The objective of the authors was to provide an up-to-date review about the epidemiology, diagnosis, and surgical management of the malignant primary sacral tumors. METHODS A PubMed search was conducted using a combination of the following items: (('Spinal Neoplasms'[Mesh]) AND 'Sacrum'[Mesh]) NOT ('Metastasis' OR 'Metastases' OR 'Benign'). The literature review and the author's own...

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ژورنال

عنوان ژورنال: Medicine

سال: 2018

ISSN: 0025-7974,1536-5964

DOI: 10.1097/md.0000000000013796